| abstract |
Benzo[b]thiophenes of the formula I or a pharmaceutically acceptable salt or solvate thereof are used in the manufacture of a medicament for inhibiting plasminogen activator inhibitor-1 in a warm blooded animal. In formula I: R1 and R3 are independently H, alkyl, -CO-alkyl or -CH2-Ar or -CO-Ar; Ar is optionally substituted phenyl and R2 is pyrrolidine, hexamethyleneimino, or piperidino. |