| abstract |
pharmaceutical composition comprising as the active ingredient a pyrrole derivative represented by general formula (1), a pharmaceutically acceptable salt thereof or a solvate thereof same is claimed wherein: R1 represents hydrogen or alkoxycarbonylamino; R2 represents alkyl, optionally substituted aryl, an optionally substituted aromatic heterocycle, amino, mono-alkyl amino, di-alkyl amino or optionally substituted cyclic amino; R3 represents cyano or carbamoyl; R4 represents hydrogen or alkyl; E represents alkylene; q is 0 or 1 and A represents methyl, optionally substituted aryl or an optionally substituted aromatic heterocycle. The medicinal composition is efficacious in treating frequent urination or urinary incontinence. Also claimed is the compound of formula I limited by the provisos as defined in the specification. |