| abstract |
The use of a compound of formula I for the manufacture of a medicament for the inhibition of phosphdiesterase type IV or the production of tumour necreosis. R3 is an optionally substituted aryl, heteroaryl or alkyl group; R4 is bicyclo[2.2.1]hept-2-yl group or a phenyl group optionally substituted in the 3 and/or 4 positions with a group selected from fluoro, chloro, methoxy, trifluoromethyl, cyano, carboxy, methylcarbamoyl, dimethyl-carbamoyl or carbo(C1-C4)alkoxy |