abstract |
This invention relates to microorganisms which can utilize an N-protected proline derivative of the general formula (I) in the form of the racemate or one of its optically active isomers, wherein R 1 is - (CH 2) 2 -COOH, or optionally substituted in each case, C1-6 alkoxy, aryl or aryloxy, and R2 means hydrogen or hydroxy, as the only nitrogen source, the only carbon source or the only carbon and nitrogen source. These microorganisms can be used in a process for the preparation of N-protected cyclic or aliphatic D-amino acid derivatives of general formulas (II) and (V), wherein A together with -N- and -CH- and R3, R4 and R5 have the given meanings. |