| abstract |
The present invention relates to methods for inhibiting herpes replication and for treating herpes infection in a mammal by inhibiting the herpes helicase primase enzyme complex. The present invention also relates to thiazolylphenyl derivatives of formula (G) which inhibit herpes helicase primase and pharmaceutical compositions comprising the thiazolylphenyl derivatives, methods of use and methods of preparing the thiazolylphenyl derivatives. In formula (G), R and Z are as defined in the specification, where Z is the characteristic feature. |