| abstract |
Compounds, Preparations and Methods for Inhibiting Interleukin-10 Protease Activity. The compounds, α-substituted acetamides have formula (A) r COOR2 R13 N-N-COCHCH2> H where: (A) r2 = H or alkyl; r) = halogen, 0 (CO) o in aryl, OPOR ^ rS ¦ "'- ^ o"> o ^. "N R * (b) where: R" * and r5 = aryl; r6 = H, aryl or aralkyl; r7 = independently selected from r6, CF3 and CF2CF3; R 6 = r 6 -CO, heteroaryl-CO, heteroaralkyl-CO and amino acid. |