http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NO-932275-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J- |
| filingDate | 1993-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feae499433b1097200af8b0c3d1e8a52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e6bc68e99581dda96e24985994563a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ce03a7e9cf1ad5bc2715426546982f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd20afaa85c8284db8c30cea00698a9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b069e9e8e64752866e9835f5e1ca4400 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66a6fc4b24bc915e3b31b4d62629bf68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d67fb2f5da667a32487c3f925ab4975b |
| publicationDate | 1993-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NO-932275-L |
| titleOfInvention | 14BETA-H, 14- AND 15-EN-11BETA-ARYL-4-EESTRENES |
| abstract | New compounds of general formula (I) as well as their pharmacologically acceptable addition salts with acids are described. In formula (I), R11 in either (1a) represents a hydrogen atom at the p-position, while R12 and R13 each represent a hydrogen atom, or (lb) R11 represents a hydrogen atom at the p-position, while R12 and R13 together represent a second bond, or (Ic) R 11 and R: 2 together represent a second bond, while R 13 represents a hydrogen atom, or (Id) R 11 represents a hydrogen atom in the α-position, while R 12 and R 13 together represent a second bond. In all cases (1a, 1b, Ic or Id), X represents an oxygen atom, the hydroxymino group> N ~ OH or two hydrogen atoms, R 1 represents a hydrogen atom or a methyl group; R 2 represents a hydroxy group, a C 1 -C 2 alkoxy or C 1 -C 2 acyloxy group, while R 3 and R 1 have the usual meanings for competing pregesterone antagonists set forth in the specification. Also described are processes for the preparation of these novel compounds, pharmaceutical preparations containing these compounds, their use in the manufacture of drugs, and novel intermediates necessary for this process. These new compounds have strong affinity for the progestagen receptor, as well as strong antigenic, antiglucocorticoid, antimineral corticoid and antiandrogenic properties. |
| priorityDate | 1990-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.