http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NO-921683-L
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 1992-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a242defa6f3edd8166d9a0baa225442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9e1bb40c09bc6fe279bdeb1a50a05a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35dced24adc6411940b70e645d69c061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5587939776feb9eb37b50b359b98381 |
publicationDate | 1992-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NO-921683-L |
titleOfInvention | MEMBRANEOUS PROBLEMS |
abstract | An oligonucleotide probe compound comprising a nylon membrane having a high density of anionic carboxyl groups, to which membrane at least one oligonucleotide probe containing a 5'-amine is covalently bonded via an amide bond and a method of bonding the oligonucleotide probe to the nylon. The simple 5 'end binding of the oligonucleotides to the membrane surface leaves the probe free to react with complementary sequences, thereby increasing hybridization efficiency over probes bound by methods using heat or ultraviolet light for immobilization. The simplicity and reproducibility of this method and the sensitivity obtained when the compounds prepared by the method are used are ideal for the use of the method and compounds for the diagnosis of infectious and genetic diseases, analysis of mutations in neoplasias, performance of HLA typing and other applications. |
priorityDate | 1991-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
---|---|
isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458397365 |
Total number of triples: 21.