| abstract |
2-R2-3-R3-6-PY-5-Q-3H-imidazo [4,5-b] pyridines of the formula :. or 1 - ^ - 2 - ^ - 6-PY-5-Q-1H-imidazo [4,5-b] pyridines of the formula :. or pharmaceutically acceptable acid addition salts thereof, wherein Q 1 and R 2 are each hydrogen or lower alkyl, R 1 and R 2 are each hydrogen, lower alkyl, lower hydroxyalkyl, 2,3-dihydroxypropyl, lower alkoxyalkyl or Y carbon atoms between its bonding bonds and NB are di- (lower alkyl) amino or 4-morpholinyl, at least one of R-. or R is hydrogen, and PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower alkyl substituents, which compounds are useful as cardiotonic agents, prepared by reacting 2-RNH-3-RNH-5- PY-6-Q-pyridine (II) with a tri- (lower alkyl) ortho- (lower alkanoate). |