http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NO-330010-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dee3727dba91e4e7aa3b26ce9efbcc21 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 |
| filingDate | 2005-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a60880e25219bb940467fe9ea25ec9b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb5dc69d9048ea3aead0bfc8e3430c56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e33c19618f133aeaf9a7a4f1bf711871 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98972285ecb547f4bb4445282e86157f |
| publicationDate | 2011-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NO-330010-B1 |
| titleOfInvention | Novel derivatives of pyridylethanol (phenylethyl) amines as inhibitors of cholesterol biosynthesis, processes for their preparation, use of the compounds and pharmaceutical preparations containing them |
| abstract | New derivatives of pyridylethanol (phenylethyl) amines of formula I are described, wherein n is an integer from 1 to 4, R 1 is a hydrogen atom, hydroxyl group or lower C 1-6 alkoxy group, R 2 is a hydrogen atom or a straight or branched lower C 1-6 alkyl group, X is hydrogen, fluorine, chlorine, bromine, hydroxyl group, trifluoromethyl group, 3,4-di-Cl, 2,4-di-C1 or lower C1-6 alkoxy group, the enantiomers, diastereomers or racemates thereof or the physiologically acceptable acid addition salts thereof , which are ligands of the sigmoid receptors for inhibiting cholesterol biosynthesis and thus are suitable for the treatment of hypercholesterolemia and hyperlipemia in humans. The largest decrease in cholesterol was observed with 1- (3-pyridyl) -2- (N- (2- (3,4-dicholorophenyl) ethyl-N-propylamino) ethanol in the form of the dihydrobromide salt (signature BK-35. 2HBr) . |
| priorityDate | 2002-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.