| abstract |
wherein Z 1 is (CH 2) q or C = O; Z 2 is (CH 2) P or C = O; D is -CH = or C = O or (CH 2) m where m is 0,1,2 or 3; n = 0.1 or 2; q = 1 or 2; q = 0.1 or 2; Q is C or N; A is (CH2) X where x is 1 to 5 or A is (CH2) X ', where x1 is 1 to 5 with an allcenyl bond or an alkynyl bond sitting anywhere in the chain, or A is - (CH2 ) X2-O- (CH2) X3- where x2 is 0 to 5 and x3 is 0 to 5, provided that at least one of x2 and x3 is different from 0; B is a bond or is (CH 2) x 4 where x 4 is 1 to 5; X is CH or N; X 2 is C, N, O or S; X 3 is C, N, O or S; X 4 is C, N, O or S; X 5 is C, N, O or S; X 6 is C, N, O or S; provided that at least one of X2, X3, X4 X5 and X6 is N; and at least one of X 2, X 3, X 4 X 5 and X 6 is C. R 1 is rather alkyl; R 2 is H, alkyl, alkoxy, halogen, amino, substituted amino or cyano; R 2a, R 2b and R 2c may be the same or different and are selected from H, alkyl, alkoxy, halogen, amino, substituted amino or cyano; and r3, E, Z and Y are as defined herein. |