| abstract |
Heterocyclically substituted tricyclic compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein: ni and now independently are 0-2, Het is an optionally substituted mono-, di- or tricyclic heteroaromatic group, B is alkyl or optionally substituted alkenyl, R -COR or a carboxy, sulfinyl, sulfonyl, sulfonamide or amino acid derivative, R substituted alkyl, R, R, R, R, and Rer as defined in the specification are disclosed in addition to pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure and cancer, by administering said compounds. |