http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NO-20080359-L
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B63-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 |
filingDate | 2008-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02a02a19757b09826fc9edcc59ae2d0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c75f07838a8a23c74523afb6436a2ab3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2c79da2755884bc6e22efd9d4985008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8471d45fa9c1955864c3972769c6a753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07a691965dbbf09af93f80a97787406e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a0d1d1e66cb9fbfa08d851f02e975b3 |
publicationDate | 2008-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NO-20080359-L |
titleOfInvention | Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base |
abstract | The present invention relates to the crystalline base of the well-known antidepressant drug escitalopram, S-1- [3- (dimethylamino) propyl] -1- (4-fluorophenyl) -1,3-dihydro-5-isobezofurancarbonitrile, formulations of said base, a process for preparing purified salts of escitalopram, such as the oxalate, using the base, the salts obtained by said process and formulations containing such salts, and a process for preparing purified escitalopram free base or salts of escitalopram, such as the oxalate, using the hydrobromide, the salts obtained by said process and formulations containing such salts. Finally, the present invention relates to an orodispersible tablet having a hardness of at least 22 N and an oral disintegration time of less than 120 seconds and comprising one active pharmaceutical ingredient adsorbed on a water-soluble filler wherein the active pharmaceutical ingredient has a melting point in the range of 40-100. ° C as well as a process for preparing an orodispersible tablet. |
priorityDate | 2005-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.