http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NO-20080359-L

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filingDate 2008-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02a02a19757b09826fc9edcc59ae2d0d
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publicationDate 2008-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NO-20080359-L
titleOfInvention Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
abstract The present invention relates to the crystalline base of the well-known antidepressant drug escitalopram, S-1- [3- (dimethylamino) propyl] -1- (4-fluorophenyl) -1,3-dihydro-5-isobezofurancarbonitrile, formulations of said base, a process for preparing purified salts of escitalopram, such as the oxalate, using the base, the salts obtained by said process and formulations containing such salts, and a process for preparing purified escitalopram free base or salts of escitalopram, such as the oxalate, using the hydrobromide, the salts obtained by said process and formulations containing such salts. Finally, the present invention relates to an orodispersible tablet having a hardness of at least 22 N and an oral disintegration time of less than 120 seconds and comprising one active pharmaceutical ingredient adsorbed on a water-soluble filler wherein the active pharmaceutical ingredient has a melting point in the range of 40-100. ° C as well as a process for preparing an orodispersible tablet.
priorityDate 2005-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 31.