| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_516fdf3a7f5bd547b2d9ae14dd8fa9ec |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
2007-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60cd1dc384393e64865093d324c2b537
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a3b3029d6cefd5a39c4cba229be745c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e6b6ce2fb5ac1c306a6719a89fe9901
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ea12aa91655a8eb89cf5263cce3be8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8809ae94e8f0a23d2bfb1191c798395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b4fb3a29693cb2da63fb3dd78cdeb2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7102954e1a235b373b796941e1061d42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2f8ab19776b48e25abb560ffd1611b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30f7c7ef57246f550427515ffb0aa172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acb1c3ef13ed2188531521c85ff8c302 |
| publicationDate |
2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NO-20076339-L |
| titleOfInvention |
Bovine ABCG2 gene miss mutations and uses thereof |
| abstract |
A quantitative trait locus (QTL) to influence milk, fat and protein concentration was located to a 4cM confidence interval on chromosome 6 centered on microsatellite BM143. The genes and sequence variation in this region were characterized and common haplotypes spanning five polymorphic sites in the genes IBSP, SPP1, PKD2 and ABCG2 for two progenitor heterozygotes for this QTL were located. Expression of SPP1 and ABCG2 in bovine mammary gland increased from birth through lactation. SPP1 was sequenced and all the coding exons of ABCG2 and PKD2 were sequenced for these two progenitors. the single nucleotide change capable of encoding a substitution of tyrosine-581 to serine (Y581S) in ABCG2 transporter was the only polymorphism corresponding to the segregation status of all three heterozygous and 15 homozygous progenitors for QTL in Israeli and US Holstein populations. |
| priorityDate |
2005-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |