| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-429
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-424
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-429
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-424
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate |
2007-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0b9509efe4a4c35528ac9fbb5a339e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198a34864813377b660eefb82cf18f70 |
| publicationDate |
2008-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NO-20076076-L |
| titleOfInvention |
Bicyclic 6-alkylidene penems as class D beta-lactamase inhibitors |
| abstract |
The present invention relates to certain biscyclic 6-alkylidene penems which act as an inhibitor of class D enzymes. Lactamases hydrolyze? -lactam antibiotics and serve as such as the primary cause of bacterial resistance. The compounds of the present invention when combined with lactam antibiotics will provide effective treatment against life-threatening bacterial infections. In accordance with the present invention, compounds of the general formula I or a pharmaceutically acceptable salt or in vivo hydrolyzable ester R5 thereof are provided: wherein: one of A and B represents hydrogen and the other an optionally substituted condensed bicyclic heteroaryl group; and X = O or S. (I) |
| priorityDate |
2005-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |