| abstract |
Compounds of the formula I structure include pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL cholesterol, lowering LDL cholesterol and for treating or preventing atherosclerosis. In the compounds of formula I, B or R 2 is a phenyl group having an orthoaryl, -heterocyclyl, -benzoheterocyclyl or -benzocycloalkyl substituent, and another position in the five-membered ring has an aromatic substituent, heterocyclic substituent, cycloalkyl substituent, substituent or benzocycloalkyl substituent coupled directly to the ring or coupled to the ring via a -CH 2 group. |