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filingDate 2006-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NO-20065422-L
titleOfInvention Delivery of anti-fungal drug
abstract An improved anti-fungal composition for topical application to the skin or nails comprises: (1) an allylamine antifungal compound; (2) an aliphatic alcohol substituted with an aromatic substituent wherein the allylamine antifungal compound is soluble to such a degree that a therapeutically effective concentration of the allylamine antifungal compound can be applied topically in solution; (3) a lower aliphatic alcohol in which the aromatic alcohol is soluble; and (d) water or a water-compatible solvent mixture. The allylamine antifungal compound may be terbinafine or naphthipine. The aliphatic alcohol substituted with an aromatic substituent may be benzyl alcohol or phenethyl alcohol. The lower aliphatic alcohol may be ethyl alcohol or isopropyl alcohol. In an alternative, the composition may further comprise a further anti-fungal compound. Another feature is a method of treating a fungal infection of the skin or nails which comprises administering the antifungal composition topically to the skin or nails in an amount therapeutically effective in treating the fungal infection.
priorityDate 2004-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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