http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NO-20065181-L

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filingDate 2006-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdc4de4beb501afde2a4989330d8e630
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publicationDate 2006-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NO-20065181-L
titleOfInvention Stereoselective bioconversion of aliphatic dinitriles to cyanocarboxyls
abstract The present invention relates to a regio- and stereoselective bioconversion of selected alicalic dinitriles to the corresponding cyanocarboxylic acids. More particularly, the present invention provides methods for converting 2-isobutyl-succinonitrile to (S) -3-cyano-5-methylhexanoic acid, which is a useful intermediate in the synthesis of (S) -3-animinomethyl-5-methylhexanoic acid (pregabalin). Pregabaiin can be used to treat certain celebrity diseases, such as treating and preventing stroke, pain and psychotic disorders.
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Total number of triples: 30.