abstract |
The present invention relates to carboxylic acids of formula (I) and their use in the treatment and / or prevention of overweight and / or metabolic events mediated by insulin resistance or hyperglycemia comprising Type I and / or II diabetes, insufficient glucose tolerance, insulin resistance, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia and polycystic ovarian syndrome (PCOS). The invention relates in particular to the use of carboxylic acids of formula (I) to modulate, then specifically inhibit, the activity of PTP. |