| abstract |
The present invention relates to optically active, heteroaromatic (-hydroxy esters of formula (I): useful in the synthesis of epo-tilone derivatives of ( chiral metal catalyst or a microbiological or enzymatic reduction, as well as processes for preparing them (I), wherein: A is a bicyclic, heteroaromatic residue of formula (A): wherein "heteroaromatic" represents a heteroaromatic ring with five or six members and up to two heteroatoms selected from oxygen, nitrogen and sulfur, which are optionally substituted |