| abstract |
Sustained release dosage forms for twice daily dosing to a human patient are described to provide pain relief. The sustained release dosage forms include an immediate release component and a sustained release component, collectively containing a therapeutically effective amount of an opioid analgesic and a therapeutically effective amount of a non-opioid analgesic. In a preferred embodiment, the non-opioid analgesic is acetaminophen, and the opioid analgesic is hydrocodone and pharmaceutically acceptable salts thereof, and in a particularly preferred embodiment, the pharinasuitically acceptable salt is bitartrate. |