| abstract |
Amide type carboxamide derivatives of general formula [1]: wherein X is -N = or -CH =; R 1 is halogen, lower alkyl, etc; R 2 has the formula [2] Y 1 and Y 2 are the same or different and are halogen or a group selected from lower alkyl, lower alkoxy, etc .; and ring A is phenyl etc. Pharmacologically acceptable salts of the derivative are also described. The derivative and salts are useful as medicine, especially as an FXa inhibitor. where X is -N = or -CH =; R 1 is halogen, lower alkyl, etc; R 2 has the formula [2] Y 1 and Y 2 are the same or different and are halogen or a group selected from lower alkyl, lower alkoxy, etc .; and ring A is phenyl etc. Pharmacologically acceptable salts of the derivative are also described. The derivative and salts are useful as medicine, especially as an FXa inhibitor. |