| abstract |
Compounds of formula (I) are described wherein R 1 and R 2 together with the nitrogen atom to which they are attached form an optionally substituted heterocyclic ring, X is S, NR "or CH 2, R and R 'are hydrogen or specified substituents and R" is a specified substituent. The compounds are useful as inhibitors of kinase-ATM (ataxia-telangiectasia mutated), especially in the treatment of cancer and retrovirally mediated diseases. |