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filingDate 2005-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2005-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NO-20051232-L
titleOfInvention Topical anhydrous and ethanol-free ascomycin compositions
abstract Single phase topical liquid or semi-solid pharmaceutical compositions substantially free of ethanol and water comprising an ascomycin, such as pimecrolimus, in a carrier vehicle comprising a 3-component solvent composition comprising at least 40% by weight of the total weight of the composition and comprising: i) C3-8 alkanol and / or C1-8 alkanediol; ii) a fatty alcohol; and iii) a further solvent selected from: a) an alkane carboxylic acid alkyl ester and / or alkanedicarboxylic acid ester and / or b) a hydrophilic co-component and / or c) a triglyceride; and any additional conventional excipients
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