http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NO-20045528-L
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
| filingDate | 2004-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b09f0d7d671dba1cc6a5e65dd7b18a8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_450577062c3ef31ace62c2c4756ee93c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198190f7d0182c3e9890328a52ddd79a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_316935eab0702c7760a9453bd6885308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecd75786bf67819ea237e87c74b12b4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c880370536daa14836009ff5417489fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61d3e6c58e6c6df8fef5f4801018a5c3 |
| publicationDate | 2005-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NO-20045528-L |
| titleOfInvention | MHC1R antagonists |
| abstract | The present invention relates to compounds of formula I wherein R 1 represents a C 1-4 alkoxy group optionally substituted with one or more fluorine atoms or a C 1-4 alkyl group optionally substituted with one or more fluorine atoms; n represents 0 or 1; R 2 represents a C 1-4 alkyl group optionally substituted with one or more fluorine atoms or a C 1-4 alkoxy group optionally substituted with one or more fluorine atoms; m represents 0 or 1; R 3 represents H or a C 1-4 alkyl group; L1 represents an alkylene chain (CH2) r wherein r represents 2 or 3, or L1 represents a cyclohexyl group wherein the two nitrogen atoms bearing R3 and R4, respectively, are bonded to the cyclohexyl group either via the 1,3 or 1,4 positions of the cyclohexyl group or L1 represents a cyclopentyl group wherein the two nitrogen atoms bearing R3 and R4 are respectively linked to the cyclopentyl group via the 1,3-position of the cyclopentyl group and in addition when R5 represents 9,10-methanoanthracene-9 (10H) -yl represents the group L1 N (R4) - together a piperidyl ring bonded to L2 through the piperidinyl nitrogen and to N-R3 via the 4-position of the piperidyl ring, with the proviso that when R5 represents 9,10-methanoanthracen-9 (10H) -yl, then is r only 2; R 4 represents H or a C 1-4 alkyl group optionally substituted by one or more of the following: an aryl group or a heteroaryl group; L 2 represents a bond or an alkylene chain (CH 2) s where s represents 1, 2 or 3 wherein the alkylene chain is optionally substituted by one or more of the following: a C 1-4 alkyl group, phenyl or heteroaryl; R 5 represents aryl, a heterocyclic group or a C 3-8 cycloalkyl group optionally fused to a phenyl or to a heteroaryl group; as well as optical isomers and racemates thereof, as well as pharmaceutically acceptable salts thereof, subject to a process for the preparation of such compounds, their use in the treatment of obesity, psychiatric disorders, cognitive disorders, memory disorders, schizophrenia, epilepsy and related disorders and neurological disorders such as dementia, multiple sclerosis, Parkinson's disease, Huntington's chorea and Alzheimer's disease and pain-related disorders, and pharmaceutical preparations containing them. |
| priorityDate | 2002-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.