abstract |
There is disclosed a compound represented by the formula wherein ring M is a heterocyclic ring, wherein ¿X = Y <is one of -N = C <, -CO-N <or - CS-N <; Ra and Rb are bonded to each other to form ring A, or they are the same or different and independently represent a hydrogen atom or substituent on ring M; ring A and ring B independently represent an optionally substituted homocyclic or heterocyclic ring, with the proviso that at least one of them is an optionally substituted heterocyclic ring; ring C is an optionally substituted homocyclic or heterocyclic ring; ring Z is an optionally substituted nitrogen-containing heterocyclic ring; and n is an integer from 1 to 6, or a salt thereof which has a tachykinin receptor antagonistic effect in vitro and is useful for the prevention or treatment of depression, anxiety, manic depressive illness or psychopathy. |