http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NO-172492-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1fb708f306656bd0392ced86025446e1 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- |
filingDate | 1991-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cbd635c80bbbfe968ae90a3bf66496b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc85dbbdff3c13c230ef8582bc08a628 |
publicationDate | 1993-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NO-172492-B |
titleOfInvention | PROCEDURE FOR THE PREPARATION OF ALKALIMETAL OR EARTHALKALIMETAL SALTS OF N5-FORMYL-5,6,7,8-TETRAHYDROPHOLIC ACID |
abstract | Alkali metal or alkaline earth metal salts of N 5 -formyl-5,6,7,8-tetrahydrofolic acid are obtained by mixing 5,6,7,8-tetrahydrofolic acid with at least one solvent and this mixture is mixed with the formula as formylating agent and heated to a temperature at 45 ° C to 75 ° C. After the formylation, the mixture is diluted with water and mixed with a corresponding alkali metal or ordalkali metal base in such an amount that a measured pH of 7.5 to 10.0 is obtained. To this mixture, which corresponds to 1 part by volume, is added 1.5 to 3 parts by volume of at least one polar, water-miscible organic solvent. The precipitated alkali metal or alkaline earth metal salt of N-formyl-5,6,7,8-tetrahydrofolic acid is separated and recrystallized from water. |
priorityDate | 1990-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.