| abstract |
Novel imidazo [1,5-a] pyridine derivatives of formula I. or their 5,6,7,8-tetrahydro derivatives ,. which means hydrogen,. halogen, lower alkyl,. lower alkoxy, hydroxy. or aryl lower alkoxy,. wherein aryl is phenyl or with lower alkoxy, lower alkyl, halogen or trifluoromethyl mono- or di-substituted phenyl, R represents hydrogen, halogen or lower lower alkyl, C means carboxy, lower. alkoxy carbonyl, unsubstituted, mono- or di-lower alkyl-substituted carbamoyl, cyano, formyl ,. hydroxymethyl, 5-tetrazolyl, unsubstituted or. with lower alkyl substituted 4,5-dihydro-2-oxazolyl, or hydroxycarbamoyl, and. (a) A means unsubstituted or lower alkyl. substituted ethenylene (vinylene) and B means alkylene. with 1-12 C atoms, alkinylene or alkenylene with. 2-12 C atoms, phenylene-lower alkylene, phenylene-lower alkylene, phenylene, phenylene- (thio or oxy) -lower alkylene, or (b) A means a bond and B means lower alkylene-. phenylene, phenylene-lower alkylene, phenylene, lower alkylene- (thio or oxy) -lower alkylene, lower alkylene- (thio or oxy) -phenylene, phenylene- (thio or oxy) -lower alkylene, phenylene-lower alkylene, lower alkylene The invention further relates to the process for the preparation of these compounds, their use and to pharmaceutical compositions containing these compounds. . |