abstract |
Compsn. is applied to the oral cavity or vagina and contains a cpd. (I) of 5-aminosalicylic acid (ASA) and its derivs. (I) is present in amt. of 0.1-25 wt.% in liq. compsns. or in an amt. of 0.1-500 mg per solid dosage unit. Compsns. pref. contain ASA and have a pH of 3-9.5, adjusted with MHCO3, M2CO3 or MOH (M = Na or K). Compsns. are formulated as mouthwashes, vaginal douches, sprays, tablets, pastilles or chewing gum. Pref. mouth spray comprises 0.1-25g ASA, 1-20g xylitol, 0.1-0.5g peppermint flavour, 5-15g EtOH and H2O to 100ml, under isobutane pressure. |