http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-8101469-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a333e6344b62fb21a7c1ee592b165fca |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-675 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 |
| filingDate | 1981-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1982-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NL-8101469-A |
| titleOfInvention | NEW CYCLOHESEYL ESTERS OF MOMIC ACID AND PHARMACEUTICAL PREPARATIONS CONTAINING SUCH A COMPOUND AND METHOD FOR PREPARING THESE COMPOUNDS. |
| abstract | (A) 3-Methyl(-3-R1-5-R2-cyclohexyl mandelate esters of formula (I) are new. (where one of R1 and R2 is Me and the other is COOH or CH2OH). (B) Intermediates of formula (III) and (IV) (see below) are also new. (I) have circulatory activity, i.e. they have vasodilatory, cholelitholytic and anti-arteriosclerotic activity and promote blood circulation and new capillary formation. They also have spasmolytic activity. Effective daily doses are 50-2000 mg. (I) may be prepd. by reacting Ph-CO-COx with (III) to give (IV) and reducing latter to give (I) (where one of R'1 and R'2 is Me, and the other is COOH; X is an opt. reactively modified COOH gp.). |
| priorityDate | 1981-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.