http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-8100293-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7cc0afde3fcfa1b157a2f61f94fa212f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-13 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-84 |
| filingDate | 1981-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1982-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NL-8100293-A |
| titleOfInvention | NEW ANTI-ALLERGICA. |
| abstract | Azole derivs. of formula (I) and their acid addition salts are new. In (I) the dotted line indicates one double bond either position. R is H, alkenyl, alkoxy, alkyl, alkenyloxy, aryloxy, aralkoxy, halo, cyano, nitro, carboxy, hydroxy, formyl, carbalkoxy, hydroxyalkyl, amino, alkylamino, trifluoromethyl, mercapto, trifluoromethoxy, alkylthio or aminoalkyl. Y is N, NR2 or CR2. R2 is H, alkyl or aryl, and when Y is NH, then (R)a is not H. a is 1-4. Xand Z are each oxygen, sulphur, NR2 or CR2, but where Y is NR2, X is not CR2. R1 is H, alkyl, aryl, acyl, alkoxycarbonyl or aryloxycarbonyl. All aromatic gps. have up to 10C and all alkyl, alkenyl etc. up to 7C. (I) have antiallergic activity by inhibition of mediator release. The usual daily dose is 10-750 mg per day. A specific cpd. is 2-(2-oxo-3H-1,3,4-oxadiazol-5-yl) benzoxazole and its 1-methyl; 5-chloro and 6-methyl analogues. |
| priorityDate | 1981-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.