http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-7808801-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-68
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
filingDate 1978-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc585d6aab0ecd0525e37d271766ddb1
publicationDate 1979-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NL-7808801-A
titleOfInvention BENZOTHIAZOLINONE DERIVATIVES WITH PHARMACOLOGICAL ACTION.
abstract Processes for (a) preparing pharmaceutical compsns. contg benzothiazole or benzimidazole derivs. of formula (I) and (b) preparing cpds. (I) themselves are claimed: (where Z is S or 1-6C alkylimino, R1 is H, halogen, 1-6C alkyl, 1-6C alkoxy or CF3, R2 is 1-6C alkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, hydroxyalkoxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, Ar of ANR4R5, Ar is phenyl opt. substd. by halogen, OH, 1-6C alkyl, 1-6C alkoxy and/or 1-6C alkanoyl, A is 1-6c alkylene, R4 and R5 are 1-6C alkyl, cyclohexyl or phenyl, or NR4R5 is morpholino)1/2 Cpds. (I) have anti-inflammatory and antiarrhythmic activity. In an example, 4'-ethoxy-5-CF3-2-oxobenzothiazoline-3-acetanilide is prepd. from 5-CF3-2(3H)-benzothiazolinone and 4'-ethoxy-2-chloro-acetanilide.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4673746-A
priorityDate 1967-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 27.