http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-7808801-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
filingDate | 1978-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc585d6aab0ecd0525e37d271766ddb1 |
publicationDate | 1979-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NL-7808801-A |
titleOfInvention | BENZOTHIAZOLINONE DERIVATIVES WITH PHARMACOLOGICAL ACTION. |
abstract | Processes for (a) preparing pharmaceutical compsns. contg benzothiazole or benzimidazole derivs. of formula (I) and (b) preparing cpds. (I) themselves are claimed: (where Z is S or 1-6C alkylimino, R1 is H, halogen, 1-6C alkyl, 1-6C alkoxy or CF3, R2 is 1-6C alkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, hydroxyalkoxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, Ar of ANR4R5, Ar is phenyl opt. substd. by halogen, OH, 1-6C alkyl, 1-6C alkoxy and/or 1-6C alkanoyl, A is 1-6c alkylene, R4 and R5 are 1-6C alkyl, cyclohexyl or phenyl, or NR4R5 is morpholino)1/2 Cpds. (I) have anti-inflammatory and antiarrhythmic activity. In an example, 4'-ethoxy-5-CF3-2-oxobenzothiazoline-3-acetanilide is prepd. from 5-CF3-2(3H)-benzothiazolinone and 4'-ethoxy-2-chloro-acetanilide. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4673746-A |
priorityDate | 1967-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.