http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-7605380-A

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5304
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-58
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66
filingDate 1976-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1977-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NL-7605380-A
titleOfInvention PROCEDURE FOR PREPARING FOSFINYL DERIVATIVES AND PROCEDURE FOR PREPARING A MEDICINAL PRODUCT WITH ANALGETIC AND / OR ANTI-INFLAMMATORY ACTION BASED ON THIS.
abstract Phosphinyl derivs. of formula (I): (X is CH or N; R1 = phenyl or quinolyl both opt. substd. by halo; CF3 or 1-3C alkyl gp. with together is not >4C; R2 = a dialkylphosphinyl gp. with its terminal gps. CH3, opt. substd. in the alkylene residue by an OH and having in total 3-7C). are prepd. e.g. by reacting corresp. acids or their usual reactive derivs. with R2OH. (I) have analgesic anti-inflammatory and anti-rheumatic activities without side effects. They have adequate water solubility and for 8 cpds. quoted the LD50 (p.o mice) is from 596 to >3000 mg/kg.
priorityDate 1976-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458394811

Total number of triples: 20.