http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-7215455-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 |
filingDate | 1972-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1974-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NL-7215455-A |
titleOfInvention | 9-beta-d-arabinofuranosyl-adenine 3',5'-cyclo monophosphate - - antiviral cpd,and its intermediates |
abstract | The title cpd., which is active against Herpes simplex types 1 and 2, Vaccinia, myxomatosis virus and pseudorabies virus, is prepd. by substituting an 8-halo-adenosine 3',5'-cyclomonophosphate in the 2-position with a leaving gp., treating this cpd. with CH3OOH and CH3CONa to give 2'-O-(leaving gp.)-8-hydroxy-adenosine 3',5'-cyclomonophosphate, treating this cpd. (e.g. with methanolic NH4PH to give 8-2'-anhydro-8-oxy-9 beta-D-arabinofuranosyl-adenine 3',5'-cyclomonophosphate, treating this cpd. with liquid H2S to give 8-mercapto-9 beta-D-arabinofuranosyl-adenine 3',5'-cyclomonophosphate, and converting this to the title cpd., e.g. by redn. with Raney Ni. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0015584-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0015584-A3 |
priorityDate | 1972-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 15.