http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-2027371-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3868745a86f52a211bd9026c293ebae8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a43334fc3bd3ee4717dfb04ad842045 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 |
| filingDate | 2021-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b717a69cacf2fb65e793414abeede8d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a4a43e8f0b0297e32d577918eed93e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7fcfb38ce5257267907f9269fd4224a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5bf790a5f55fc28225296d01de25aa4 |
| publicationDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NL-2027371-B1 |
| titleOfInvention | Injectable cushioning hydrogels |
| abstract | The invention relates to a kit of parts, consisting of compositions (Cl) and (C2) in separate containers, for use in the treatment or prevention of osteoarthritis in a vertebrate, wherein: (a) composition (C1) is a liquid hydrogel formulation comprising a polymer gellant with chemically cross-linkable groups; (b) composition (C2) is an aqueous auxiliary formulation comprising either one or more dissolved cross-linkers Z having two or more reactive groups that can chemically cross-link the polymer gellant by forming covalent bonds, or comprising one or more dissolved compounds Y, selected from the group consisting of oxidant, oxidase, peroxidase and combinations thereof, that initiate or mediate chemical cross-linking of the polymer gellant, wherein said treatment comprises combining compositions (C l) and (C2) to form a liquid hydrogel composition (C3) and administering said liquid hydrogel composition (C3) to the synovial fluid or to the cavity of a synovial joint of the vertebrate, to form a cross- linked hydrogel (C4) in the synovial joint of the vertebrate, or wherein said treatment comprises in a first step administering one of the compositions (C1) or (C2) to the synovial fluid or to the cavity of a synovial joint of the vertebrate and in a second step administering the other of the compositions (C1) or (C2), to form a liquid hydrogel composition (C3) in the synovial joint of the vertebrate that reacts to a cross- linked hydrogel (C4). |
| priorityDate | 2021-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 347.