http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-2022905-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d69445b2bef2798628ddc9a3f83d0174 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 |
| filingDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c87a33c496e91a2d8984b3981237e25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeedc0c40c4a0f10fcce30316202ae9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4b2555ce6463aba773a0e74f83498cc |
| publicationDate | 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NL-2022905-B1 |
| titleOfInvention | Yeast with engineered Molybdenum co-factor biosynthesis |
| abstract | The present invention relates to a yeast comprising a Moco pathway gene set that allows said yeast to produce Molybdenum co-factor and its variants bis-Mo-molybdopterin guanine 5 dinucleotide, sulfurated molybdenum co-factor and Mo-molybdopterin cytosine dinucleotide. Preferably the Moco pathway gene set comprises a gene encoding a GTP 3',8—cyclase; a gene encoding a Cyclic pyranopterin monophosphate synthase; a gene encoding a Molybdopterin synthase catalytic subunit; a gene encoding a Molybdopterin synthase sulfur carrier subunit; a gene encoding a Molybdopterin adenylyltransferase; a gene encoding a 10 Molybdopterin-synthase adenylyltransferase and/or a Molybdopterin molybdenumtransferase; and/or a gene encoding a Cysteine desulfurase. Preferably, the Moco-modifying gene set comprises a gene encoding a Molybdenum cofactor guanylyltransferase and a Molybdopterin-guanine dinucleotide biosynthesis adapter protein to form bis-molybdopterin guanine dinucleotide; a Molybdenum co-factor sulfurase to form sulfurated Molybdenum co- 15 factor and/or a Molybdenum co-factor cytidylyltransferase to form Molybdopterin cytosine dinucleotide. |
| priorityDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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