abstract |
The invention provides compounds, pharmaceutical compositions comprising these compounds, and methods of using such compounds in order to treat or prevent diseases or disorders associated with abnormal or poorly regulated kinase activity, particularly of Ros, KDR, FMS, c-FMS, FLT3, c-Kit, JAK2, JAK3, Aurora, PDGFR, Lck, TrkA, TrkB, TrkC, IGF-IR, ALK4, ALK5, and ALK, or combinations thereof. |