http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NI-201000049-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b9d212083c297d5c75d3b97ac90a50f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-12 |
| filingDate | 2010-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52cedee0e70d8b04aa364165855bc824 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4009135bdebd217d1a772c2e1b40138 |
| publicationDate | 2010-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NI-201000049-A |
| titleOfInvention | METHOD TO PRODUCE 2'-DEOXY-5-AZACITIDINE (DECITABIN) |
| abstract | Method for producing 2'-deoxy-5-azacytidine (Decitabine) providing a compound of formula (I), wherein R is a removable substituent known per se; and R1 is a removable substituent; also providing a silylated base formula (II), in which R2 is a protecting group, preferably a trimethylsilyl residue (TMS); reacting the compound of formula (I) and the compound of formula (II) together in a suitable anhydrous solvent and in the presence of a suitable catalyst; and eliminating the R substituents from the compound obtained to obtain the compound 2'-deoxy-5-azacytidine (Decitabine), characterized in that said catalyst is selected from the group comprising an aliphatic sulfonic acid salt or a salt of a strong inorganic acid. |
| priorityDate | 2007-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.