| abstract |
Substituted benzoxaboroles whose structure comprises Formula III, wherein R3 is selected from ?CH3, ?CH2CH3, ?CH2=CH2, ?CH2CH2CH3, ?CH(CH3)2, ?CH2CH2=CH2, and cyclopropyl, R1 and R2 are each independently selected from H, -CH3, -CH2CH3, ?CH2CH2CH3, and ?CH(CH3)2; compositions containing such compounds, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided. |