| abstract |
A COMPOUND REPRESENTED BY FORMULA (I) OR A PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF, WHICH CAN INHIBIT A FIBROBLAST GROWTH FACTOR RECEPTOR (FGFR) FAMILY KINASE IN CANCER TISSUES. (IN THE FORMULA, A REPRESENTS A 5-TO 10-MEMBERED HETEROARYL GROUP, OR A C₆₋₁₀ ARYL GROUP; R₁ AND R₂ INDEPENDENTLY REPRESENT H, OH, X, CN, NO₂, A C₁₋₄ HALOALKYL GROUP, A C₁₋₆ ALKYL GROUP, OR THE LIKE <R₁ AND R₂ TOGETHER FORM A (SUBSTITUTED) 3- TO 10-MEMBERED HETEROCYCLYL GROUP OR A (SUBSTITUTED) 5 TO 10-MEMBERED HETEROARYL GROUP>; R₃ REPRESENTS H, A C₁₋₅ ALKYL GROUP, A C₆₋₁₀ ARYL GROUP, A C₁₋₅ ALKYL GROUP, OR A C₁₋₄ HALOALKYL GROUP; AND R₄ REPRESENTS H, X, A C₁₋₃ ALKYL GROUP, A C₁₋₄ HALOALKYL GROUP, OH, CN, NO₂, OR THE LIKE.) |