| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0771ae88b2a6d09ee67adcaa5a65c4d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-838
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-877 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y401-03004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-0301
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1025 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88 |
| filingDate |
2010-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8d31d59a192118d964310975a207112 |
| publicationDate |
2017-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MY-159420-A |
| titleOfInvention |
Method for the enzymatic production of 3-hydroxy-3 methylbutyric acid from acetone and acetyl coa |
| abstract |
DESCRIBED IS A METHOD FOR THE PRODUCTION OF 3-HYDROXY-3-METHYIBUTYRIC ACID (ALSO REFERRED TO AS BETA-HYDROXYISOVALERATE OR HIV) FROM ACETONE AND A COMPOUND WHICH PROVIDES AN ACTIVATED ACETYL GROUP COMPRISING THE ENZYMATIC CONVERSION OF ACETONE AND A COMPOUND WHICH PROVIDES AN ACTIVATED ACETYL GROUP INTO 3-HYDROXY-3-METHYLBUTYRIC ACID. THE CONVERSION MAKES USE OF AN ENZYME WHICH IS CAPABLE OF CATALYZING THE FORMATION OF COVALENT BOND BETWEEN THE CARBON ATOM OF THE OXO (I.E. THE C=O) GROUP OF ACETONE AND THE METHYL GROUP OF THE COMPOUND WHICH PROVIDES AN ACTIVATED ACETYL GROUP. PREFERABLY, THE ENZYME EMPLOYED IN THE PROCESS IS AN ENZYME WITH THE ACTIVITY OF A HMG COA SYNTHASE (EC 2.3.3.10) AND/OR A PKSG PROTEIN AND/OR AN ENZYME WITH THE ACTIVITY OF A C-C BOND CLEAVAGE/CONDENSATION LYASE, SUCH AS A HMG COA LYASE (EC 4.1 .3.4) ALSO DESCRIBED ARE ORGANISMS WHICH ARE ABLE TO PRODUCE 3-HYDROXY-3-METHYLBUTYRIC ACID FROM ACETONE, A COMPOUND WHICH PROVIDES AN ACTIVATED ACETYL GROUP, THE USE OF THE ABOVE-MENTIONED ENZYMES AND ORGANISMS FOR THE PRODUCTION OF 3-HYDROXY-3-METHYLBUTYRIC ACID AS WELL AS THE USE OF ACETONE FOR THE PRODUCTION OF 3-HYDROXY-3-METHYLBUTYRIC ACID. (FIGURE 5) |
| priorityDate |
2009-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |