| abstract |
THE INVENTION RELATES TO BIOCHEMICAL SYNTHESIS OF 6-AMINO CAPROIC ACID FROM 6-AMINOHEX-2-ENOIC ACID COMPOUND OR FROM 6-AMINO-2-HYDROXYHEXANOIC ACID, BY TREATMENT WITH AN ENZYME HAVING α ,β-ENOATE REDUCTASE ACTIVITY TOWARDS MOLECULES CONTAINING AN α, β-ENOATE GROUP AND A PRIMARY AMINO GROUP. THE INVENTION ALSO RELATES TO PROCESSES FOR OBTAINING SUITABLE GENETICALLY ENGINEERED STRAINS FOR BEING USED IN SUCH BIOTRANSFORMATION PROCESS, AND TO PRECURSOR FERMENTATION OF 6-AMINO CAPROIC ACID FROM INTERMEDIATES LEADING TO 6-AMINO CAPROIC ACID. FINALLY, THE INVENTION RELATES TO CERTAIN NOVEL BIOCHEMICALLY PRODUCED COMPOUNDS, NAMELY 6-AMINOHEX-2-ENOIC ACID, 6-AMINOHEXANOIC ACID, AS WELL AS TO CAPROLACTAM PRODUCED THEREFROM AND TO NYLON-6 AND OTHER DERIVATIVES PRODUCED FROM SUCH BIOCHEMICALLY PRODUCED COMPOUNDS OR CAPROLACTAM. |