| abstract |
A PROCESS FOR PREPARING 5- {4-[2-(N-METHYL-N-(2-PYRIDYL)AMINO)ETHOXY]BENZYL} -2,4- THIAZOLIDINEDIONE, OR A TAUTOMERIC FORM THEREOF OR A SALT THEREOF, OR A SOLVATE THEREOF WHICH PROCESS COMPRISES, TREATING 5-{4-[2-(N-METHYL-N-(2- PYRIDYL)AMINO)ETHOXY}BENZYLIDENE) -2,4-THIAZOLIDINEDIONE OR A TAUTOMERIC FORM THEREOF OR A SALT THEREOF, OR A SOLVATE THEREOF. WITH A COMPLEX HYDRIDE REDUCING AGENT OR A SOURCE OF A COMPLEX HYDRIDE REDUCING AGENT ; AND THEREAFTER, AS REQUIRED, PREPARING A PHARMACEUTICALLY ACCEPTABLE SALT, OR A PHARMACEUTICALLY ACCEPTABLE SOLVATE OF THE COMPOUND 5-{4-[2-(N-METHYL-N-(2-PYRIDYL)AMINO)ETHOXY]BENZYL}-2,4- THIAZOLIDINEDIONE OR A TAUTOMERIC FORM THEREOF AND A NOVEL INTERMEDIATE FOR USE IN THE PROCESS. |