| abstract |
THE PRESENT INVENTION RELATES TO NOVEL AFFINITY LIGAND-MATRIX CONJUGATES COMPRISING A LIGAND WITH THE GENERAL FORMULA (A) WHICH LIGAND IS ATTACHED TO A SUPPORT MATRIX IN POSITION (A), OPTIONALLY THROUGH A SPACER ARM INTERPOSED BETWEEN THE MATRIX AND LIGAND. THE INVENTION FURTHERMORE RELATES TO THESE NOVEL AFFINITY LIGAND-MATRIX CONJUGATES AND THE PREPARATION AND USE THEREOF IN THE PURIFICATION OF PROTEINACEOUS MATERIALS SUCH AS E.G IMMUNOGLOBULINS, INSULINS, FACTOR VII, OR HUMAN GROWTH HORMONE OR ANALOGUES, DERIVATIVES AND FRAGMENTS THEREOF AND PRECURSORS. |