| abstract |
A MUTANT OF AN EXTRACELLULAR ENZYME-PRODUCING MICROORGANISM BELONGING TO GENUS BACILLUS, WHICH IS RESISTANT TO A CELL MEMBRANE SYNTHESIS INHIBITOR, INCLUDING VANCOMYCIN AND RISTOCETIN, IS DISCLOSED. THE CELL MEMBRANE SYNTHESIS INHIBITOR-RESISTANT MUTANT CAN PRODUCE SUCH AN ENZYME AS CELLULASE, PROTEASE, OR AMYLASE ABOUT 2 TO 4 TIMES OF THE PARENT STRAIN. SUCH A MUTANT CAN BE PRODUCED BY SUBJECTING AN EXTRACELLULAR ENZYME-PRODUCING MICROORGANISM TO A MUTATION TREATMENT, AND CULTURING SAID MICROORGANISM IN A CULTURE MEDIUM CONTAINING A CELL MEMBRANE SYNTHESIS INHIBITOR. |