http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-PA99011826-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2eb7163c43f7e5c8a870f30f7f1cd5ea |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 |
| filingDate | 1998-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdef79e2ad8fc9186c4b77575a4ef9c4 |
| publicationDate | 2002-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-PA99011826-A |
| titleOfInvention | POLYLYLAMIINE POLYMERS FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA. |
| abstract | The invention relates to the unsuspected discovery that a new class of ion exchange resins have better bile desalk sequestration properties that result in reduced dosages, which improves tolerance and acceptance by the patient, thereby improving the palatability of the composition, and they are relatively easy to manufacture. The polymers used in the invention consist of non-absorbable and eventually crosslinked polyamines, as defined herein. The properties of the polymer that gave rise to the present invention were discovered during clinical tests of the polymer for use in phosphate binding in patients with hyperphosphatemia. The polyamines of the invention are characterized by one or more monomer units of formula (1) and their salts, where n is a positive integer and x is 0 or an integer between 1 and about 4. The polymer can be characterized by the substantial absence of one or more alkylated amine monomers and / or the substantial absence of one or more alkyl trialkylammonium groups. In preferred embodiments, the polymer is crosslinked by means of a multifunctional crosslinking agent. |
| priorityDate | 1997-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.