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filingDate 1996-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c43091536b45fdd1d682c5d16c6f3d06
publicationDate 2004-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-PA97009909-A
titleOfInvention MODIFIED OSTEOGENIC MATERIALS.
abstract A process and product comprising collagen and demineralized bone particles; the product may contain a maximum of 20% by weight of inorganic material; the product can be densified by compression; Additional osteogenic factors, mitogens, drugs or antibiotics can be incorporated therein; Inorganic materials can be attached to the organic matrix through precoating with a protein, peptide or amino acid binding to calcium or hydroxyapatite; the materials also display long-term drug release characteristics; The subject of this invention is a resulting method and composition that increases the speed and predictability of osteoinduction by demineralized bone matrix; in particular, this invention relates to demineralized bone compositions and salts of calcium or other mineral that show increased osteogenic potential; The invention also relates to osteogenic compositions comprising between about 60% to 90% by weight of demineralized bone and compositions comprising a vehicle and alkaline phosphatase capable of inducing bone-like structures.
priorityDate 1995-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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