abstract |
A composition comprising particles containing at least about 95% of the weight of amphotericin B, in which the particles have an average mass diameter ranging from about 1.1 im to about 1.9 pm. Another composition also including particles containing at least about 95% of the weight of amphotericin B, in which at least about 80% of the weight of the particles have a geometric diameter that varies from about 1.1 pm to about 1 , 9 pm. And also another composition that includes particles with amphotericin B, in which the particles have an average mass diameter of less than about 1.9 pm and in which amphotericin B has a crystallinity level of at least about twenty%. Unit dosage forms, delivery systems and methods may involve similar compositions. |