| abstract |
The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I); wherein the substituents are as defined in the specification, to procedures for their production, their use as pharmaceuticals and to pharmaceutical compositions that comprise them. Formula (I), wherein A represents O, or N (R1); Y represents a group of the formula, or where the left link is attached to group A and the right link being to group R; R represents an aryl of 5 to 10 substituted or unsubstituted carbon atoms, heteroaryl of 5 to 10 substituted or unsubstituted carbon atoms, heteroaryl of 5 to 10 substituted or unsubstituted carbon atoms, a group N (R1) (R4 ), or an N (R2) group (CHP3R4); R represents hydrogen, alkyl of 1 to 4 carbon atoms or CF3; R2 represents hydrogen, alkyl of 1 to 4 carbon atoms or CF3; R3 represents hydrogen, alkyl of 1 to 4 carbon atoms or CF3; R4 represents an aryl of 5 to 10 substituted or unsubstituted carbon atoms or a heteroaryl of 5 to 10 substituted or unsubstituted carbon atoms; in the form of a free base or in the form of acid addition salt. |