abstract |
A compound of formula I is provided (see formula I): wherein X, R1, R2, R3, R4, R5, R6, R7 and R8 have meanings given in the description, and pharmaceutically acceptable salts thereof, whose compounds are useful. in the treatment of diseases in which microsomal prostaglandin E synthase-1 activity is desired and / or required, and in particular in the treatment of inflammation. |